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diyhrt.market/transfem-hrt-guide.html
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@@ -255,7 +255,7 @@ Standard Adult Female Range: 0.8-3.1 nmol/L<br>
<p>While other administration methods will see large variations throughout the day and a huge spread from person to person in what dose is required to reach certain levels, injections provide highly stable and predictable results. This makes recommended starting doses and judging blood tests very simple, perfect for DIY where many are paying out-of-pocket for every test and trying to minimise how many are needed.</p>
<p>Lastly, <a href="meds/groups/estradiol-injections.html">it&rsquo;s cheap</a>. DIY injectables are almost always homebrew and 2 years of supplies can easily be bought for around $150. Many in our community struggle financially, given the importance of HRT this cheapness is life and death for many.</p>
<h4 id="transdermal-gel-plus-blockers">Transdermal Gel + Blockers</h4>
<p>Transdermal gels are rubbed on the skin and absorbed within a few minutes, done daily. This is combined with an oral blocker also taken daily, usually <a href="meds/groups/cyproterone.html">Cyproterone Acetate</a> though <a href="https://diyhrt.market/meds/groups/bicalutamide">Bicalutamide</a> or <a href="meds/groups/spironolactone.html">Spironolactone</a> work well too.</p>
<p>Transdermal gels are rubbed on the skin and absorbed within a few minutes, done daily. This is combined with an oral blocker also taken daily, usually <a href="meds/groups/cyproterone.html">Cyproterone Acetate</a> though <a href="meds/groups/bicalutamide.html">Bicalutamide</a> or <a href="meds/groups/spironolactone.html">Spironolactone</a> work well too.</p>
<p>While it lacks the stability and predictable dosages of injections it has no problem achieving good enough levels and avoids the liver conversion issues of pills. Theoretically, monotherapy is practical with gel but in practice the margin of error for letting them get too low is so thin that it&rsquo;s not taking the chance. Miss your dose by half a day or get into a habit of spreading it too thin and you can find your Testosterone levels starting to rise again.</p>
<p>It&rsquo;s also physically safer since no needles are involved and <a href="meds/groups/estradiol-gels.html">similarly cheap</a> since Gels are increasingly sold by the same homebrew providers that make the injectables.</p>
<p>A starting Estradiol dose of 3-4mg/day will work for most though this should be tweaked in response to blood tests. For blockers 12.5mg/day Cyproterone, 50mg/day Bicalutamide or 200mg Spironolactone will do the job, no testing necessary.</p>
@@ -353,7 +353,7 @@ Standard Adult Female Range: 0.8-3.1 nmol/L<br>
<p>Finasteride is an effective method of treating male pattern baldness, a concern naturally important to transgender individuals interested in feminising HRT, however it should be understood that given the suppression of Testosterone and overall Androgen levels by Estrogens and/or other Antiandrogens, it is largely unnecessary as a component of feminising HRT regimen.</p>
<h2 id="homebrew-vs-pharmaceuticals">&ldquo;Homebrew&rdquo; vs Pharmaceuticals</h2>
<p>Homebrew drugs are manufactured by individuals or small groups of trans people looking to do their part to help the community. These groups will purchase Estradiol or another active ingredient from a wholesale supplier in its raw powder form and manufacture it into whatever form is ultimately taken by a person such as an injectable oil, a swallowable pill, etc. It&rsquo;s important to understand the risks, there is a non-zero possibility of contamination or problems with the manufacturing process because these folks simply do not have the same resources that a multi-million dollar pharmaceutical company has.</p>
<p>On the other hand, the most trusted suppliers are eminently educated on these subjects often working in or adjacent to the pharmaceutical industry, or at the very least operating on guidance from others who are. If you&rsquo;re interested in reading more about this the guidance at <a href="https://hrt.cat/">hrt.cat</a> explains in intricate detail every single aspect of the process and most suppliers have a process largely comparable to that. At diyhrt.market we can vouch for having had this reviewed by a professional in the biomedical industry. Sites like this one and <a href="https://diyhrt.cafe/">diyhrt.cafe</a> vet suppliers, making sure there are months worth of satisfactory feedback from customers before listing anything from them. There have in the past been a very small handful of suppliers who have not reached that quality bar and been rejected by the community, so we know this community consensus approach works.</p>
<p>On the other hand, the most trusted suppliers are eminently educated on these subjects often working in or adjacent to the pharmaceutical industry, or at the very least operating on guidance from others who are. If you&rsquo;re interested in reading more about this the guidance at <a href="https://hrtcafe.net/Homebrew/injection-tutorial.html"></a><a>hrtcafe.net</a> explains in intricate detail every single aspect of the process and most suppliers have a process largely comparable to that. At diyhrt.market we can vouch for having had this reviewed by a professional in the biomedical industry. Sites like this one and <a href="https://diyhrt.cafe/">diyhrt.cafe</a> vet suppliers, making sure there are months worth of satisfactory feedback from customers before listing anything from them. There have in the past been a very small handful of suppliers who have not reached that quality bar and been rejected by the community, so we know this community consensus approach works.</p>
<p>Put simply, homebrew drugs from suppliers listed here are safe and effective within the constraints of reasonable concerns, but we do believe it&rsquo;s important that you know what you&rsquo;re getting.</p>
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@@ -387,5 +387,5 @@ DIYHRT.Market 2022-2024
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